| Issue |
Natl Sci Open
Volume 1, Number 1, 2022
Special Topic: COVID-19: Virus, Immunity and Vaccines
|
|
|---|---|---|
| Article Number | 2021004 | |
| Number of page(s) | 6 | |
| Section | Life Sciences and Medicine | |
| DOI | https://doi.org/10.1360/nso/20220001 | |
| Published online | 24 March 2022 | |
PERSPECTIVES
Cell-in-cell: an Emerging Player in COVID-19 and Immune Disorders
1
Beijing Institute of Biotechnology, Academy of Military Medical Sciences, 20 Dongda Street, Beijing 100071, China
2
Research Unit of Cell Death Mechanism, Chinese Academy of Medical Science, 2020RU00920 Dongda Street, Beijing 100071, China
* Corresponding author. E-mail: sunq@bmi.ac.cn
Received: 1 December 2021
Accepted: 30 December 2021
Cell-in-cell is a unique phenomenon mostly documented in human cancer tissues. A recent study demonstrated that cell-in-cell might promote lymphopenia by internalizing and killing immune cells in COVID-19, which implicates cell-in-cell as an emerging player in a broader spectrum of pathological processes, such as immune dysregulation.
Key words: cell-in-cell / cell death / COVID-19 / lymphopenia / immune dysregulation
© The Author(s) 2022. Published by China Science Publishing & Media Ltd. and EDP Sciences.
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