Natl Sci Open
Volume 2, Number 5, 2023
Special Topic: Gene Editing towards Translation
|Number of page(s)||21|
|Section||Life Sciences and Medicine|
|Published online||07 July 2023|
Molecular breeding of farm animals through gene editing
State Key Laboratory of Animal Biotech Breeding, College of Biological Sciences, National Engineering Laboratory for Animal Breeding, Frontiers Science Center for Molecular Design Breeding, China Agricultural University, Beijing 100193, China
2 College of Animal Science and Technology, China Agricultural University, Beijing 100193, China
3 Sanya Institute of China Agricultural University, Sanya 572025, China
4 Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China
* Corresponding author (email: firstname.lastname@example.org)
Revised: 9 February 2023
Accepted: 14 February 2023
The rapid development of biotechnology has facilitated our understanding of the biological functions of candidate genes for important economic traits in farm animals. Molecular breeding by gene editing has greatly revolutionized the breeding of farm animals. Through gene editing and embryo manipulation, breeds with designed economic or disease-resistant traits can be readily generated. Along with this fast progress, the safety assessment of gene-edited farm animals has attracted public and regulatory attention. This review summarizes the research progress of gene editing in farm animals, focusing on performance improvement, disease resistance, bioreactors, animal welfare, and environmental friendliness. The limitations and future development of gene editing technology in farm animal breeding are also discussed.
Key words: molecular breeding / farm animals / gene editing
© The Author(s) 2023. Published by Science Press and EDP Sciences.
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